PROGRAMMA FINALE - ABSTRACTS ONLINE

POSTER SESSIONS ABSTRACTS

Poster Session VI
P-6 AGING PHARMACOLOGY AND PAIN PHARMACOLOGY

 

P-6/1 Adult hippocampal neurogenesis and cortical gliogenesis in APP mutant mice
T. Ed Dami, A. Fiorentini, I. Luccarini, C. Traini, C. Grossi, F. Casamenti (Florence)
P-6/2 Role of Natural Antioxidant Compounds as Potential Pharmacological Countermeasures against Skeletal Muscle Impairment Due to Aging Process
S. Pierno, A. Liantonio, G. Gramegna, A. Mele, D. Tricarico, J-F. Rolland, M. Cannone, L. Villanova, D. Conte Camerino (Bari)
P-6/3 Sulforaphane improves motor impairments and protects against neuron death in a mouse model of Parkinson’s disease.
F. Morroni, A. Tarozzi, C. Bolondi , J.M. Zolezzi Moraga, G. Cantelli Forti , P. Hrelia (Bologna)
P-6/4 Involvement of opioid and cannabinoid receptors in the oxytocin-induced antihyperalgesic effect following ICV administration
R. Russo, G. La Rana, G. D'Agostino, R. Meli, A. Calignano ( Napoli)
P-6/5 Involvement of protein kinase C in neuronal regeneration in a model of antiretroviral-induced painful peripheral neuropathy in mice.
M.D. Sanna , N. Galeotti, C. Ghelardini (Firenze)
P-6/6 Analgesic properties of N-(1-carbamoyl-2-phenyl-ethyl)butyramide a new synthetic butyrate prodrug in a model of acute and visceral pain
R. Russo, G. D'Agostino, A. Iacono, G. Mattace Raso, R. Meli, R. Berni Canani, A. Calignano (Napoli)
P-6/7 Effect of MCP-1 synthesis inhibitors in a rat model of incisional pain
A. di Matteo, A. Amato, W. Castaldi, D. Mattei, B. Garrone, A. Guglielmotti (Rome)
P-6/8 Oxaliplatin elicits mechanical and cold allodynia in rodents via TRPA1 receptor stimulation
G. De Siena, S. Harrison, S. Materazzi, N. Moretto, P. Failli, D. Preti, N. Marchetti , A. Cavazzini , F. Mancini , P. Pedretti, R. Patacchini , P. Geppetti, R. Nassini (Firenze, Parma, Ferrara)
P-6/9 NCX 1236, a novel gabapentin endowed of nitric oxide-releasing properties, reverses the development of mechanical allodynia in streptozotocin-treated diabetic mice
V. Borghi, F. Impagnatiello, P.A. Borea, F. Vincenzi, M. Targa, E. Ongini, K. Varani (Milano, Ferrara)
P-6/10 Analgesic activity of new hybrid muscarinic agonists in mice
L. Flammini, S. Bertoni, F. Saccani, A. Rapalli, V. Arcaro, G. Domenichini, E. Barocelli (Parma)
P-6/11 Endomorphin-1 analogues as novel and highly selective MOPr agonists: design and characterization of innovative analgesic drugs
A. Bedini, L. Gentilucci, R. De Marco, S. Spampinato ( Bologna)
P-6/12 Protective effects of antioxidants during acute inflammatory pain: the role of 4-Hydroxynonenal, an endogenous aldehyde
C. Muscoli, C. Dagostino, F. Lauro, S. Ilari, D. Ventrice, E. Vizza, F. Casale, M. Scalzo, M. Rizzo, N. Costa, M.C. Strongoli, E. Palma, D. Salvemini, V. Mollace (Catanzaro, Caatanzaro, Roma, Catania, St Louis)
P-6/13 Activation of Kv7 potassium channels inhibits intracellular Ca2+ increases triggered by pain-inducing compounds in sensory neurons
P. Ambrosino, M.V. Soldovieri, D. Presutti, M. Taglialatela (Campobasso, Napoli, Campobasso)
P-6/14 Anti-hyperalgesic and anti-edematogenic effects of ARN0077, an irreversible inhibitor of N-acylethanolamine-hydrolyzing acid amidase (NAAA), in a murine model of persistent pain
O. Sasso, P. Busquet, D. Piomelli, R. Bertorelli , A. Reggiani (Genova)
P-6/15 Metabotropic glutamate receptor subtype 8 in the amygdala: a novel target for inflammatory pain relief
E. Palazzo, I. Marabese, L. Luongo, C. Giordano, S. Boccella, V. de Novellis, F. Rossi, S. Maione (Naples)
P-6/16 Salvinorin A reduce formalin-induced allodynia through spinal glial/microglial phenotypical changes in mice.
F. Guida , M. De Chiaro, G. Aviello, L. Luongo, A. Izzo, R. Capasso , M.A. Scafuro, V. de Novellis, S. Maione ( Naples)
P-6/17 Involvement of the endocannabinoid/endovanilloid system in the morphofunctional changes occurring in the pre-limbic/infra-limbic (PL/IL) cortex in neuropathic rats
L. Gatta, S. Boccella , D. Vita, L. Luongo, G. Bellini, M. De Chiaro, I. Marabese, D. Siniscalco, F. Piscitelli, V. Di Marzo, E. Palazzo , F. Rossi, S. Maione, V. de Novellis (Naples)
P-6/18 Long lasting effects of human mesenchymal stem cell systemic administration on pain-like behaviours, cellular and biomolecular modifications in neuropathic mice
D. Siniscalco, C. Giordano, L. Luongo, F. Rossi, S. Maione, V. de Novellis (Naples)
P-6/19 The galactosylation of Nω-nitro-L-arginine enhances its anti-nocifensive or anti allodynic effects by targeting glia in healthy and neuropathic mice
C. Giordano, D. Siniscalco, D. Melisi, L. Luongo, A. Curcio, E. Palazzo, I. Marabese, M. De Chiaro, M.G. Rimoli, S. Maione, V. de Novellis (Naples)
P-6/20 mGlu7 receptor in the striatum decrease nociceptive responses in neuropathic rats
I. Marabese, E. Palazzo, M. De Chiaro , L. Luongo, F. Guida, S. Boccella, C. Giordano, S. Maione, V. de Novellis, V. de Novellis (Naples)
P-6/21 Peptide and non-peptide PKR antagonists as novel analgesics
D. Maftei, R. Lattanzi, V. Noviello, L.A. Giancotti, G. Balboni, L. Negri (Roma, Cagliari)
P-6/22 Intravenous human adipose stem cells reverse neuropathic pain symptoms and restore pro-anti inflammatory cytokine balance in the chronic constriction injury murine model
A. Rossi, E. Arrigoni, S. Niada, S. Franchi, M. Colleoni, A.E. Panerai, P. Sacerdote, A.T. Brini (Milano, MIlano)
P-6/23 Umbellulone, the Irritant Principle of the Headache Tree (Umbellularia Californica), Stimulates the Trigeminovascular System via TRPA1 activation
R. Nassini, G. De Siena , C. Avonto, G. Appendino, G. La Marca, P. Geppetti, S. Benemei , S. Materazzi (Firenze , Novara)
P-6/24 Oxaliplatin-induced neuropathy: oxidative stress as pathological mechanism. In vivo evidences
L. Bonaccini, L. Di Cesare Mannelli, M. Zanardelli, P. Failli, C. Ghelardini (Firenze)
P-6/25 PC1, a prokineticin receptor antagonist, displays anti-inflammatory effects greater than that of indomethacin
L.A. Giancotti, R. Lattanzi, P. Spinsanti, M. Canestrelli, D. Maftei, G. Balboni, S. Salvadori, L. Negri (Roma, Cagliari, Ferrara)
P-6/26 Discovery And Pharmacological Evaluation Of A New Family Of TRPA1 Antagonists.
P. Pedretti, C. Fusi, D. Preti, S. Materazzi, R. Nassini , P.G. Baraldi, P. Geppetti (Firenze, Ferrara)