Sessioni Poster


Neuropharmacology

Mercoledì 28 Ottobre 2015 / 13.00-14.00
1Intrathecal baclofen: pharmacological activities leading to innovative uses and unexpected adverse reactions
Pozzi M., Piccinini L., Gallo M., Motta F., Giordano F., Turconi AC., Clementi E., Radice S.
3In vitro pharmacological characterization of novel nociceptin/orphanin FQ receptor ligands
Ferrari F., Cerlesi MC., Ruzza C., Malfacini D., Rizzi A., Asth L., Gavioli EC., Guerrini R., Zaveri N., Calò G.
35Perampanel effects in the WAG/Rij rat model of epileptogenesis, absence epilepsy and comorbid depressive-like behaviour
Citraro R., Leo A., Aiello R., Marra R., De Sarro G., Russo E.
39Fingolimod shows antiepileptogenic and anti anxiety/depressive effects in Wag/Rij rats, a well established model of absence epilepsy and neuropsychiatric comorbidities
Leo A., Citraro R., Chimirri S., Scicchitano F., De Sarro G., Russo E.
51ku0063794, a dual mtorc1 and mtorc2 inhibitor, reduces neural tissue damage and locomotor impairment after spinal cord injury in mice
Paterniti I., Impellizzeri D., Cordaro M., Siracusa R., Esposito E., Cuzzocrea S.
55Knocking Down mGluR1 Prolongs Survival And Ameliorates Motor Skills in the SOD1G93A Mouse Model Of ALS
Gallia E., Milanese M., Puliti A., Conti F., Bonifacino T., Cattaneo L., Rossi PIA., Musante I., Melone M., Bonanno G.
56Synaptic Mechanisms Sustaining The Excessive And Precocious Glutamate Release In The Spinal Cord Of SOD1G93A Mice
Bonifacino T., Milanese M., Musazzi L., Gallia E., Cattaneo L., Treccano G., Onofri F., Popoli M., Bonanno G.
66Neuroprotection by Bexarotene in Mice Subjected to Focal Cerebral Ischemia Involves Modulation of the Immune System
Certo M., Amantea D., Endo Y., Sakurada S., Bagetta G.
90Astrocytic clasmatodendrosis, autofluorescent deposits and accumulation of Aβ-peptide? in CA1 hippocampus: possible links with aging-dependent neurodegeneration?
Lana D., Nosi D., Mercatelli R., Bucciantini M., Quercioli F., Zecchi S., Giovannini MG.
92cAMP-induced Aβ production and its role in the expression of LTP
Rebosio C., Ricciarelli R., Rivera D., Pronzato MA., Marinari UM., Puzzo D., Arancio O., Fedele E.
99Effect of co-ultramicronized PEALut treatment in a murine model of autism spectrum disorder
Crupi R., Impellizzeri D., Bruschetta G., Siracusa R., Cordaro M., Esposito E., Cuzzocrea S.
112Dysregulation of GPR17, a new key actor involved in oligodendrogenesis, in a rodent model of Multiple Sclerosis: implications for re-myelination strategies
Lecca D., Marangon D., Viganò F., Menichetti G., Fumagalli M., Bonfanti E., Furlan R., Dimou L., Abbracchio M., Coppolino GT.
119Oleuropein aglycone efficacy against Alzheimer's disease: an advanced biological preclinical investigation
Pantano D., Luccarini I., Nardiello P., Stefani M., Casamenti F.
120Role of GILZ in a mouse model of Parkinson Disease and related behavioural alterations
Leo A., Russo E., Citraro R., Mazzon E., Bruscoli S., Riccardi C., De Sarro G.
121Common miRNAs in Alzheimer’s disease and retinal degenerative diseases
Romano GL., Platania CBM., Forte S., Salomone S., Bucolo C., Drago F.
129Functional interaction between presynaptic receptors on dopaminergic and noradrenergic nerve terminals of the rat central nervous system
Padolecchia MC., Olivero G., Chen J., Grilli M., Pittaluga A., Marchi M.
141Altered social behavior and increased anxiety in the rat valproic acid model of autism: role of the endocannabinoid system
Servadio M., Melancia F., De Fulvio F., Picerno F., Cartocci V., Pallottini V., Trezza V.
143Mechanisms of GABA release from cerebellar nerve terminals: role of Na+/Ca2+ exchangers, GAT1 transporter reversal, Ca2+-induced Ca2+ release and anion channels
Raiteri L., Romei C., Milanese M., Usai C.
145Targeting the P2Y-like receptor GPR17 to foster recovery after brain ischemia
Bonfanti E., Fumagalli M., Parravicini C., Eberini I., Gelosa P., Sironi L., Cimino M., Viganò F., Dimou L., Abbracchio MP.
156NDP-α-MSH Preserves Brain Morphology and Cognitive Performance in Tg2576 Mice with Moderate Alzheimer’s Disease
Canalini F., Giuliani D., Neri L., Calevro A., Bitto A., Ottani A., Vandini E., Sena P., Altavilla A., Squadrito F., Zaffe D., Guarini S.
171Selective adenosine A2A receptor agonists and antagonists protect at different times after brain focal ischemia in the rat
Dettori I., Melani A., Cellai L., Pedata F.
181Bioenergetic effects of Clonidine on functional proteomics
Ferrari F., Gorini A., Villa RF.
185Antioxidant properties of a novel tyrosinase inhibitor on PC12 cells injured by hydrogen peroxide oxidative stress
Cossu S., Calia G., Pirisinu M., Dedola S., Rocchitta G., Delogu G., Dettori MA., Fabbri D., Serra PA., Migheli R.
187Palmitoylethanolamide increases CB2 receptor expression via PPAR-α
Giordano ME., Furiano A., Guida F., Luongo L., Romano R., Boccella S., Axerio-Cilies P., Bellini G., Alameen S., Rossi F., de Novellis V., Maione S.
192Astrocyte plasma membrane extensions are dynamically modulated by purines
Chisari M., Scuderi A., Sortino MA.
208CHF5074 (CSP-1103) induces microglia alternative activation in plaque-free tg2576 mice and primary glial cultures exposed to beta-amyloid
Porrini V., Lanzillotta A., Branca C., Benarese M., Parrella E., Lorenzini L., Calzà L., Flaibani R., Spano P., Imbimbo BP., Pizzi M.
222A new transgenic reporter mouse model for monitoring by optical imaging, in a spatial-temporal dimension, the oxidative stress in Parkinson's disease (PD)
Rizzi N., Levandis G., Cesari N., Vantaggiato C., Dell'Omo G., Blandini F., Maggi A., Ciana P.
227Astrocyte-dependent susceptibility to excitotoxicity in spermine oxidase overexpressing mouse
Venturini A., Cervetto C., Vergani L., Passalacqua M., Berretta N., D'Amelio M., Maura G., Mariottini P., Voci A., Cervelli M., Marcoli M.
239Curcumin as a potential lead compound for the development of new anti-inflammatory agents useful to treat neurodegenerative diseases
Sorrenti V., Giusti P., Zusso M.
245Early disruption of blood brain barrier integrity precedes NOX2 elevation in the social isolation rat model
Schiavone S., Mhillaj E., Tucci P., Morgese MG., Bove M., Cuomo V., Trabace L.
247Identification of microRNAs potentially regulating the expression of GPR17, a receptor involved in the development of oligodendroglial precursor cells
Marangon D., Coppolino GT., Finardi A., Furlan R., Abbracchio MP., Lecca D.
256Esculetin Protects SH-SY5Y cells Against Amyloid-Beta Induced Toxicity


Pruccoli L., Sita G., Morroni F., Hrelia P., Tarozzi A.
257Social isolation alters bone homeostasis in drug-naïve rats
Bove M., Tucci P., Mhillaj E., Morgese MG., Schiavone S., Cantatore FP., De Giorgi A., Maffulli N., Cuomo V., Trabace L.
259Soluble beta amyloid and behavioral despair: effects of several classes of antidepressants in rats
Morgese MG., Schiavone S., Tucci P., Bove M., Mhillaj E., Trabace L., Cuomo V.
262Sub-chronic celecoxib treatment prevents sAβ-induced neuroinflammation: underlying cognitive and behavioral dysfunctions
Mhillaj E., Tucci P., Morgese M.G., Furiano A., Schiavone S., Romano R., Luongo L., Maione S., Trabace L., Cuomo V.
278Effects of β-amyloid fragments on nicotinic modulation of dopamine release from rat nucleus accumbens nerve endings

Olivero G., Chen J., Padolecchia MC., Grilli M., Pittaluga A., Marchi M.
286A functional cross-talk between group-I and group-II metabotropic glutamate receptors occurs in heterologous expression systems and brain tissue
Di Menna L., Iacovelli L., Bruno V., Battaglia G., Nicoletti F.
293Tropomodulin 1 and 2 are new favorable biomarkers in high risk neuroblastoma
Bettinsoli P., Ferrari-Toninelli G., Bonini SA., Cangelosi D., Varesio L., Memo M.
298Group-I metabotropic glutamate receptor-induced stimulation of polyphosphoinositide hydrolysis is entirely mediated by mGlu1 receptors in the retina
Romano M., Mascio G., Di Menna L., Scarselli P., Biagioni F., Madonna M., Battaglia G., Bruno V., Nicoletti F.
303A functional cross-talk between alpha1-adrenergic receptors and mGlu7 metabotropic glutamate receptors may pay a role in stress-related psychiatric disorders
Iacovelli L., Di Menna L., Uschold-Schmidt N., Peterlik D., Stangl C., Molinaro G., Orlando R., Flor PJ., De Blasi A., Battaglia G., Bruno V., Nicoletti F.
305Metabotropic glutamate receptors, subtype 1, epigenetically regulate the expression of mGlu5 receptors in the cerebellum
Notartomaso S., Zappulla C., Mascio G., Motolese M., Cannella M., Scarselli P., Gradini R., Battaglia G., Bruno V., Nicoletti F.
309Oleuropein aglycone induces autophagy in vivo in a mouse model of Aß deposition and in neuroblastoma cells: a mechanistic insight
Nardiello P., Miceli C., Luccarini I., Pantano D., Stefani M., Casamenti F.
323Possible cellular mechanism of Melatonin in Spinal Cord Injury: role of PPARα
Campolo M., Paterniti I., Impellizzeri D., Cordaro M., Siracusa R., Cuzzocrea S.
324The selective antagonism of P2Y1 purinergic receptors prevents synaptic failure and affects cell proliferation induced by in vitro ischemia in rat dentate gyrus
Fusco I., Coppi E., Maraula G., Lana D., Giovannini MG., Mello T., Galli A., Pedata F., Pugliese AM.
327Involvement of Sphingosine 1 Phosphate receptor on the Blood Brain Barrier properties upon inflammatory stimuli?
Spampinato SF., Obermeier B., Cotleur A., Takeshita Y., Ransohoff RM.
329Fingolimod: a potential disease modifier in a mouse model of amyotrophic lateral sclerosis
Potenza RL., Armida M., De Simone R., Pèzzola A., Minghetti L., Popoli P.
330Palmitoylethanolamide exerts neuroprotective effects in an in vivo model of Alzheimer’s disease
Bronzuoli MR., Eivazpour S., Bartoli S., Ciconti L., Steardo L., Scuderi C.
335Comorbid depression in Alzheimer’s disease (AD): novel observations from a longitudinal study in the triple-transgenic mouse model
Lavecchia AM., Romano A., Pace L., Cassano T., Gaetani S.
336Pharmacological activation of autophagy exerts neuroprotective effects against amyloidogenic prion peptide neuronal toxicity
Thellung S., Scoti B., Corsaro A., Villa V., Nizzari M., Colucci D'Amato L., Cortese K., Birocchi F., Tacchetti C., Florio T.
338Possible dysregulation of the endocannabinoid system in a cohort of patients with Dravet syndrome
Rubio M., Valdeolivas S., Satta V., Piscitelli F., Verde R., Barroso E., Montolio M., Aras LM., Fratta W., Di Marzo V., Sagredo O., Fernandez-Ruiz J.
351Meninges harbor cells expressing neural precursor markers during development and adulthood
Pino A., Bifari F., Berton V., Kusalo M., Malpeli G., Di Chio M., Bersan E., Amato E., Scarpa A., Krampera M., Fumagalli G., Decimo I.
365Role of central histaminergic system in the analgesic and antidepressant-like effects induced by endogenous PPAR-alpha ligands in mice
Costa A., Blandina P., Ghelardini C., Passani MB., Provensi G.
389In silico identification and pharmacological evaluation of 5-Methoxyflavone as a neuroprotective agent against β-amyloid-induced toxicity
Merlo S., Basile L., Giuffrida ML., Sortino MA., Guccione S., Copani A.
393Pharmacological activation of PPAR-alpha reduces repetitive behavior in a mouse model of autism spectrum disorders
Cristiano C., D'Agostino G., Russo R., Avagliano C., De Caro C., Mattace Raso G., Meli R., Calignano A.
420NF-κB-mediated regulation of astrocyte-secreted signals modulating the differentiation potential of adult hippocampal neural progenitor cells
Cvijetic S., Bortolotto V., Marengo E., Manfredi M., Ranzato E., Canonico PL., Grilli M.
424A novel pharmacological property for ß2-adrenergic agonists
Bortolotto V., Cuccurazzu B., Crosta C., Tugnoli V., Monti D., Canonico PL., Grilli M.
426TAT-BH4 exerts a protective effect on damaged neuronal and endothelial cell
Monti M., Donnini S., Ziche M.
447Reduced Expression of mGlu5 Receptor Improves Survival and Clinical Symptoms in the SOD1G93A Mouse Model of Amyotrophic Lateral Sclerosis
Milanese M., Bonifacino T., Cattaneo L., Musante I., Gallia E., Melone M., Conti F., Puliti A., Bonanno G.
460In vivo and in vitro studies of microglia alternative activation
Pepe G., Calderazzi G., Villa A., Boraso MS., Viviani B., Vegeto E.
465Changes in HPA axis responsiveness and behavior after prenatal stress exposure and maternal separation in young male adult rats
Locci V., Biggio F., Pisu MG., Boero G., Serra M.
472Development of a new electrochemical device for the determination of dopamine auto-oxidation
Melis S., Migheli R., Serra PA., Rocchitta G.
481MPTP enhances its neurotoxicity by increasing extracellular oxygen levels in the striatum of freely-moving rats
Spano G., Bazzu G., Alvau MD., Migheli R., Rocchitta G., Serra PA.
455Pre-clinical evaluation of S48168/ARM210, a new Rycal® compound, on in vivo and ex vivo pathology-related signs of dystrophic mdx mouse
Cozzoli A., Capogrosso RF., Giustino A., Massari AM., Mantuano P., De Bellis M., Conte E., Camerino GM., Liantonio A., De Luca A.
482Involvement of the Prokineticin system in in vitro and in vivo models of Aβ-induced neurotoxicity
Marconi V., Lattanzi R., Severini C., Maftei D., Fusco I., Nisticò R., Balboni G., Ratano P., Campolongo P., Negri L.
504Hypothalamus as a pharmacologically relevant neurogenic area
Salem R., Bortolotto V., Canonico PL., Grilli M.
528Group I Metabotropic Glutamate Receptors Potentiate Glutamate Release in a Mouse Model of Amytrophic Lateral Sclerosis
Milanese M., Bonifacino T., Rossi PIA., Puliti A., Pittaluga A., Usai C., Bonanno G.
538Simultaneus agonism at NOP and antagonism at KOP receptors reduce cocaine self-administration: a potential mechanism for the effect of buprenorphine on cocaine seeking
Shen Q., Scuppa G., Ubaldi M., Stopponi S., Domi E., Ciccocioppo R.
553Role of PPAR-α and its pharmacological modulation in experimental models of Parkinson’s disease
Avagliano C., De Caro C., Russo R., Cristiano C., La Rana G., Mattace Raso G., Meli R., Calignano A.
557Neuronal PPARγ modulates anxiety-like behaviour in mice
Domi E., Soverchia L., Uhrig S., Hansson AC., Spanagel R., Ciccocioppo R., Ubaldi M.
584The PPARα agonist clofibrate reverts the cognitive impairment induced by the sub-chronic treatment with phencyclidine
Deidda M., Mameli A., Scherma M., Fattore L., Fratta W., Fadda P.
600Autophagy modulation following retinal ischemia in mice
Varano GP., Russo R., Cavaliere F., Adornetto A., Nazio F., Nucci C., Cecconi F., Morrone LA., Corasaniti MT., Bagetta G.
601Activation of astroglial calcineurin during neuronal activity and LTP
Lim D., Moccia F., Mapelli L., Genazzani AA.
613Role of central dopamine D3 and serotonin 2C receptors in the control of the mesoaccumbens dopaminergic pathway: implications for the treatment of depression
Torrisi SA., Leggio GM., Navarria A., Giurdanella G., Platania CBM., Presti D., Camillieri G., Caraci F., Bucolo C., Salomone S., Drago F.
614Orexin-A Protects Against Oxygen–Glucose Deprivation-Induced Neuronal Injury By Up-Regulating Endocannabinoid Synthesis In Primary Cortical Neurons
Palomba L., Morello G., Imperatore R., Cristino L., Di Marzo V.
618Pharmacological characterization of recombinant cell lines expressing human di-heteromeric NMDA receptors

Castelletti L., Corsi M., Virginio C., Aldegheri L., Bettini E.
630Gender and region-dependent consequences of THC adolescent exposure on behavior and synaptic plasticity
Gabaglio M., Zamberletti E., Rubino T., Parolaro D.
637Neuroprotective effects of TGF-β1 in rat retinal β-amyloid-induced damage
Giurdanella G., Fisichella V., Romano GL., Leggio GM., Platania CBM., Laudicina M., Salomone S., Caraci F., Bucolo C., Drago F.
640Epilepsy-causing mutations in Kv7.2 C-terminus affect binding and functional modulation by calmodulin

Manocchio L., Ambrosino P., Alaimo A., Bartollino S., De Maria M., Mosca I., Gomis-Perez C., Alberdi A., Scambia G., Lesca G., Villarroel A., Taglialatela M., Soldovieri MV.
646Prenatal influences facilitate the precipitation of a schizophrenia-like phenotype: Assessing the role of the endocannabinoid system
Stark T., Kucerova J., Pekarik V., Iannotti FA., Aveta T., Tabiova K., Drago F., Di Marzo V., Sulcova A., Micale V.
650NCX 667, a novel nitric oxide (NO) donor, effectively reduces intraocular pressure (IOP) in three models of ocular hypertension and glaucoma
Impagnatiello F., Storoni L., Lanzi C., Masini E., Durante M., Toris C., Ongini E., Bastia E.
677Genome-wide epigenetic analysis in knock-in mice with the human polymorphism (Val66Met) of BDNF gene
Mallei A., Corna S., Tardito D., Paiano F., Racagni G., Lee FS., Popoli M.
683Epigenetic drugs targeting acetylation of NF-KappaB and histones: a promising strategy to reduce post ischemic brain injury
Lanzillotta A., Pignataro G., Branca C., Cuomo O., Porrini V., Parrella E., Benarese M., Annunziato L., Spano PF., Pizzi M.
688The effect of melatonin in epileptogenic and neurodegenerative effects induced by palytoxin in rats
Palma E., Oppedisano F., Gliozzi M., Maiuolo J., Musolino V., Carresi C., Nucera S., Scarcella A., Giancotta C., Maretta A., Politi GB., Costa N., Muscoli C., Mollace V.
689CAP2, a regulator of actin filament dynamic, is a novel ADAM10 interactor
Pelucchi S., Musardo S., Passafaro M., Gardoni F., Marcello E., Di Luca M.
691Combinations between sulforaphane and levodopa for Parkinson's disease treatment: neuroprotective effects in in vitro and in vivo models
Tarozzi A., D'Amico M., Morroni F., Sita G., Baggiato S., Ferraro L., Hrelia P.
694Effect of oleoylethanolamide in an animal model of binge eating and in a model of reinstatement of high-fat food seeking
Giusepponi ME., Micioni Di Bonaventura MV., Romano A., Gaetani S., Cifani C.
550Apaf-1 deficient cortical neurons exhibit defects in axonal growth
De Zio D., Molinari F., Rizza S., Gatta L., Ciotti MT., Salvatore AM., Cwetsch AW., Mathiassen SG., Filomeni G., Rosano G., Ferraro E.